Fufang Lumeisu Shuan | Compound chloramphenicol suppository

[ingredients] this product is a compound preparation, each containing 0.25g of chloramphenicol, a5000 units of vitamin, and D2 500 units of vitamin.

Description

Description

[drug name]

General name: Compound Chloramphenicol suppository

English Name: Compound Chloramphenicol suppliers

Chinese Pinyin: Fufang L ǖ Meisu Chuan

[ingredients] this product is a compound preparation, each containing 0.25g of chloramphenicol, a5000 units of vitamin, and D2 500 units of vitamin.

[properties] this product is a light yellow suppository made of fatty matrix.

[indication] bacterial vaginosis.

[Specification] chloramphenicol 0.25g, vitamin a5000 unit and vitamin D2 500 unit are contained in each tablet.

[usage and dosage] vaginal administration. Once a day, after washing the vulva before going to bed at night, put one of the products into the posterior vault of the vagina.

[adverse reactions]

1. Local use may cause contact dermatitis.

2. Although the product is used locally, it can cause adverse reactions similar to systemic administration, such as aplastic anemia, due to absorption after long-term and large-scale use. If you use this product in large quantities for a long time, you should check the blood picture regularly.

3. Occasionally allergic reaction.

[taboo]

1. It is forbidden for those allergic to this product or one of its ingredients.

2. Pregnant women and lactating women should use it with caution.

[precautions]

1. This product is only for vaginal administration, do not take orally.

2. In case of allergic reaction, the drug should be stopped for medical treatment.

3. If you use too much or have serious adverse reactions, please see a doctor immediately.

4. It is forbidden to use this product when its properties change.

5. Please keep the medicine away from children.

6. If you are using other drugs, please consult a doctor or pharmacist before using this product.

[medication for pregnant women and lactating women] although this product is used locally, it may cause serious adverse reactions to newborns and lactating babies due to the severe myelosuppression effect of chloramphenicol. Therefore, pregnant women and lactating women should use it with caution.

[medication for children] it is not suitable for newborns and premature infants.

[medication for the elderly] the safety and efficacy of this product for the elderly are not clear.

[drug interaction] it has an antagonistic effect with lincomycin or erythromycin and other macrolide antibiotics, so it is not suitable for combination.

[drug overdose] is not clear.

[pharmacology and toxicology]

Mechanism of action: chloramphenicol enters bacterial cells through diffusion and binds reversibly to 50S subunit of bacterial ribosome, which hinders the growth of peptide chain (possibly due to the inhibition of transpeptidase), inhibits the formation of peptide chain and prevents the synthesis of protein, thus playing an antibacterial role.

Chloramphenicol antibacterial spectrum: aerobic gram-negative bacteria and Gram-positive bacteria, anaerobic bacteria, Rickettsia, spirochete and chlamydia. It has antibacterial activity against influenza, Streptococcus pneumoniae and meningococci. It has bacteriostatic effect on Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridis, group B streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. It is resistant to Pseudomonas aeruginosa, Acinetobacter, enterobacter, Serratia myxolyticus, proteus indole positive, methicillin resistant Staphylococcus and Enterococcus.

[pharmacokinetics] this product is topical and less absorbed by vagina.

[storage] sealed and stored in a cool and dry place (no more than 20 ℃).

[package] suppository shell belt (with medical finger sleeve attached). 8 pieces / box.

[validity period] 24 months.

[executive standard] State Drug Administration National Drug Standard ws-10001 – (hd-0264) – 2002

[approval No.] gyzz h2006552